"In the 17th century, 15,000 French immigrants bravely made their way to eastern Canada. Some headed further west, many returned to France, but a hardy few stayed in Quebec. Starting with a total of just 2,600 people between 1608 and 1760, this group would grow 800-fold over the next 10 or so generations, with little marriage outside the group. The result is the Quebec "founder" population -- a genetically homogenous group of individuals that is ideally suited to the genetic study of disease."
Read more of this fascinating article here.
My thanks to Franco-American News & Events, 4 for drawing my attention to this post.